Phytopharms of the New Paradigm
A study of pharmacologically active botanicals native to the midwestern Unites States.
An Original & Initial Forray
Leading the new paradigm into the realm of forgotten , forbidden & protected knowledge.
An Initial decree in the principle understandings of plant drugs in the new paradigm.
Knowledge of Liberation - Break the Bonds of Dominator Dependence
-An individual study of the principal alkaloids and constituents produced by the plants
-The compounds contained within the plants thought to be the primary factor of pharmacological activity.
-An analysis of the plants compounds that possess pharmacological activity will be evaluated using
chromatography & spectometry.
-Anectdotes and first hand experiences, reported historic uses in folk medicine & potential future uses.
-Human Bioassays & animal testing to establish the best route of administration and bioavailability.
-Presumptively active phytopharms and their past role in native cultures.
-A compendium of concise botanical information for use in the field, at home or in the lab.
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Ethical considerations of Native Plants and Protected Species
Safety considerations of bioassays and administration
An identifcation guide with botanical descriptions & photographs.
Traditional folk uses & medicinal values attributed by native cultures
Chemical analysis on individual species performed on multiple specimens to obtain an average constituent ratio.
Both animal & human Bioassays.
Active Constituent Profiles: Defining properties of active chemicals - Solubility - Pharmakinetics - LD50
Current Plants of Focus
Argemone alba: White Prickly Poppy.
Scirpus atrovirens: Bakana.
Cypripedium pubescens: Lady's Slipper
Corydalis aurea: There are over 300 species of the genus corydalis. Berberine, Protopine, Palmatine, tetrahydropalmatine (THP)
Dicentra canadensis:
Menispermum canadense: Moonseed
Bignonia catalpa: Bark
Asimia triloba: Seed
Rosa Canina: Root
Cornus stolinifera: Red Osier. Cambium
References and Links
USDA Agricultural Research Service: http://www.pl.barc.usda.gov/
Duke's Database: http://www.ars-grin.gov/cgi-bin/duke/farmacy2.pl